Inside a 16th-century monastery lives this classy mid-size hotel, where many original details remain intact. A fantastic location in the heart of lively Trastevere is a standout here.

Rough luxury—a five-star soul in a hip, edgy body. Design aficionados will not be disappointed by the raw aesthetics, and fans of libations will appreciate the on-site Gallery Bar, where check-ins happen, DJs spin, and a great selection of Italian wines are served.

With a reputation for having some of the largest rooms in the city, Hotel Chapter has open, urban vibes. Come and feel like a guest in a cool creative’s home, and check out the new Mexican-inspired rooftop bar upstairs, Hey Guey.

Charming and sophisticated luxury hotel with great amenities—bar, pool, gym, spa, etc.—and an elevated sense of details. Expect Carrera-covered bathrooms, delicious (and different) five-star room service, packing/unpacking service, and more.

Eight-room boutique hotel with old-world charm unique to each suite. The room service is solidly chic, and the staff (all sommeliers) know a ton about wine—make sure to request a tour of the basement cellar.

In a former palace built in the 1600s, a 21st-century renovation mixed brutalism and minimalism with natural textures and artisanal expertise to elevate this 17-room boutique hotel, equally chic and relaxing.