Inside a 16th-century monastery lives this classy mid-size hotel, where many original details remain intact. A fantastic location in the heart of lively Trastevere is a standout here.

Rough luxury—a five-star soul in a hip, edgy body. Design aficionados will not be disappointed by the raw aesthetics, and fans of libations will appreciate the on-site Gallery Bar, where check-ins happen, DJs spin, and a great selection of Italian wines are served.

With a reputation for having some of the largest rooms in the city, Hotel Chapter has open, urban vibes. Come and feel like a guest in a cool creative’s home, and check out the new Mexican-inspired rooftop bar upstairs, Hey Guey.

In a former palace built in the 1600s, a 21st-century renovation mixed brutalism and minimalism with natural textures and artisanal expertise to elevate this 17-room boutique hotel, equally chic and relaxing.

The Locarno’s design is transportive, with high ceilings, timeless vintage furnishings, and an Italian appreciation for wood and textiles that makes for a rich stay. Charm over everything here, where modern amenities take a backseat.

Contemporary design and a hotel bar worth visiting in its own right are highlights at this luxury boutique hotel with 18 rooms housed in a former mansion. Enjoy lunch in the courtyard and take advantage of the hotel’s fabulously central location in the heart of Rome.